Disorders Of The Veins And Arteries

The pathophysiology of chronic venous insufficiency and deep venous thrombosis

Advanced practice nurses often treat patients with disorders of the veins and arteries such as chronic venous insufficiency (CVI) and deep venous thrombosis (DVT). While the symptoms of both disorders are noticeable, these symptoms are sometimes mistaken for signs of other conditions, making the disorders difficult to diagnose. Nurses must examine all symptoms and rule out other potential disorders before diagnosing and prescribing treatment for patients. In this Assignment, you explore the epidemiology, pathophysiology, and clinical presentation of CVI and DVT.

To Prepare

  • Review the section “Diseases of the Veins” (pp. 598-599) in Chapter 23 of the Huether and McCance text. Identify the pathophysiology of chronic venous insufficiency and deep venous thrombosis. Consider the similarities and differences between these disorders.
  • Select a patient factor different from the one you selected in this week’s Discussion: genetics, gender, ethnicity, age, or behavior. Think about how the factor you selected might impact the pathophysiology of CVI and DVT.

To Complete

Write a 2- to 3-page paper that addresses the following:

  1. Compare the pathophysiology of chronic venous insufficiency and deep venous thrombosis. Describe how venous thrombosis is different from arterial thrombosis.
  2. Explain how the patient factor you selected might impact the pathophysiology of CVI and DVT.




Disorders of the Veins and Arteries




Student’s Name







Disorders of the Veins and Arteries

Chronic Venous Insufficiency and Deep Venous Thrombosis

The labyrinthine matrix of veins and arteries within the body is crucial to the overall health and well-being of an individual, but with the rise of a disorder within the network, the sequel can be alarming. The veins and the arteries are essential elements of the circulatory system, and they are accountable for transporting blood all around the body (Batool et al., 2020). A variety of disorders can occur when the normal functioning of the vessels is interfered with, having severe outcomes for an individual’s health. This essay will compare the pathophysiology of chronic venous insufficiency and deep venous thrombosis, describe the difference between venous thrombosis and arterial thrombosis, look at how age affects the pathophysiology of CVI and DVT, and lastly, at the diagnosis of the disorders based on age.

Chronic Venous Insufficiency Verse Deep Venous Thrombosis

Chronic venous insufficiency of the lower vehemence is associated with a broad clinical spectrum that ranges from asymptomatic but cosmetic problems to grave symptoms. Chronic venous insufficiency is a relatively common medical issue, but it is often condoned by healthcare providers due to an under appreciation of the magnitude and the effects of the issues and incomplete recognition of the various presenting affection of primary and secondary venous disorders. The main pathophysiological agency of the clinical affection of chronic venous insufficiency of the lower vehemence is ambulatory venous hypertension caused by venous valve reflux and venous flow obstruction (Youn & Lee, 2019). Deep venous thrombosis is the development of thrombosis within the deep veins of the pelvis limbs, where the pathophysiology begins in venous valve cusps, where venous thrombosis occurs in areas with minimized flow of blood, such as pockets adjacent to valves in the deep veins of the leg (Osman et al., 2018). Valves helps to promote the rate of blood flow through the venous circulation and also in potential location for venous stasis and hypoxia. Both conditions can cause swelling of the legs, but they can be distinguished by the congestion of chronic venous for chronic venous insufficiency and the formation of acute thrombus for deep venous thrombosis.

Venous Thrombosis Verse Arterial Thrombosis

Venous thrombosis occurs when the blood clot blocks a vein while arterial thrombosis occurs when the blood clots blocks an artery, where Veins and arteries carry blood from the body to the heart and from the heart to the body respectively. Venous thrombosis can be caused by injuries on the leg veins, inheriting a disorder or having certain disorders based on an individual’s genes (Northup et al., 2021), presence of an auto immune disorder that can make the blood to clot and medicines that increases the risks of blood clot. Arterial thrombosis occurs in the arteries that supplies blood to the heart muscle, and it can lead to heart attack and when arterial thrombosis occurs in a blood vessel in the brain can lead to stroke.

The Impact of Age on the Pathophysiology of CVI and DVT

Age can seriously influence the pathophysiology of chronic venous insufficiency and deep venous thrombosis, where as people age, the veins in their bodies loses their elasticity and the valves around the veins becomes weak leading to merging in the body which increases the pressure within the veins (Gujja et al., 2022). Walls of the veins can be blemished and the blood flow get impaired due to increased pressure in the veins which can lead to chronic venous insufficiency. Aged people have thicker blood which can clot easily leading to the development of deep venous thrombosis. As the vascular system change due to changes related to age can make it Difficult for the body to remove blood clots which can lead to the development of complications like pulmonary embolism.


Disorders of the veins and arteries influences an individual’s quality of life requiring prompt medication attention, chronic venous insufficiency and deep venous thrombosis have similar pathophysiology similarities, including poor blood flow and increased pressure within the veins, Venous thrombosis differs from arterial thrombosis as it affects the veins rather than the arteries. Patient factors like age can influence the pathophysiology of the disorders. The cause of deep venous thrombosis is the formation of a blood clot within the veins while for chronic venous insufficiency occurs due the damaged vein walls and weakened valves. Patient outcomes can be improved by early diagnosis and treatment of the disorders which can also prevent serious complications.










Batool, S., Nisar, M., Mangini, F., Frezza, F., & Fazio, E. (2020). Scattering of light from the systemic circulatory system. Diagnostics10(12), 1026. https://doi.org/10.3390/diagnostics10121026

Gujja, K., Kayiti, T., Sanina, C., & Wiley, J. M. (2022). Chronic venous insufficiency. Interventional Cardiology: Principles and Practice, 835-843.

Northup, P. G., Garcia‐Pagan, J. C., Garcia‐Tsao, G., Intagliata, N. M., Superina, R. A., Roberts, L. N., … & Valla, D. C. (2021). Vascular liver disorders, portal vein thrombosis, and procedural bleeding in patients with liver disease: 2020 practice guidance by the American Association for the Study of Liver Diseases. Hepatology73(1), 366-413.

Osman, A. A., Ju, W., Sun, D., & Qi, B. (2018). Deep venous thrombosis: a literature review. Int J Clin Exp Med11(3), 1551-61.

Youn, Y. J., & Lee, J. (2019). Chronic venous insufficiency and varicose veins of the lower extremities. The Korean Journal of internal medicine34(2), 269.

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