Testicular Cancer Case Studies

The development of testicular carcinoma

Testicular Cancer Case Studies A 21-year-old male noted pain in his right testicle while studying hard for his midterm college examinations. On self-examination, he noted a “grape-sized” mass in the right testicle. This finding was corroborated by his healthcare provider. This young man had a history of delayed descent of his right testicle until the age of 1 year old. Studies Results Routine laboratory studies Within normal limits (WNL) Ultrasound the testicle Solid mass, right testicle associated with calcifications HCG (human chorionic gonadotropin) 550 mIU/mL (normal: <5) CT scan of the abdomen Enlarged retroperitoneal lymph nodes CT scan of the chest Multiple pulmonary nodules Diagnostic Analysis At semester break, this young man underwent right orchiectomy. Pathology was compatible with embryonal cell carcinoma. CT-directed biopsy of the most prominent pulmonary nodule indicated embryonal cell carcinoma, compatible with metastatic testicular carcinoma. During a leave of absence from college, and after banking his sperm, this young man underwent aggressive chemotherapy. Repeat testing 12 weeks after chemotherapy showed complete resolution of the pulmonary nodules and enlarged retroperitoneal lymph nodes.

Critical Thinking Questions

1. What impact did an undescended testicle have on this young man’s risk for developing testicular cancer?

2. What might be the side effects of cytotoxic chemotherapy?

3. What was the purpose of preserving his sperm before chemotherapy?

4. Is this young man’s age typical for the development of testicular carcinoma?



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Testicular Cancer Case Studies

The Development of Testicular Carcinoma

Behind every testicular cancer diagnosis is a unique case study, a personal journey of resilience, courage, and determination to overcome the odds and reclaim one’s health. Testicular cancer is relatively rare but can have severe consequences if not detected and treated early (Rebecca et al. 129). Case studies of testicular cancer have helped researchers and clinicians understand the disease better and improve treatment options. These studies have revealed that testicular cancer typically affects younger men, with the median age at diagnosis being around 33 (Ljungman 1050). Furthermore, case studies have highlighted the importance of self-examination and early detection to improve prognosis and increase successful treatment chances. By studying the experiences of those affected by testicular cancer, researchers can continue to refine treatment protocols and develop new therapies to combat this disease. Overall, case studies of testicular cancer play a crucial role in advancing our understanding of this condition and improving patient outcomes.

Testicular carcinoma is a type of cancer originating in the testicles, the male reproductive organs responsible for producing sperm and testosterone. The exact cause of testicular carcinoma is still unknown, but certain risk factors have been identified, such as a family history of the disease, having an undescended testicle at birth, and having abnormal testicular development (Brent et al. 7). Testicular carcinoma typically begins as a small lump or swelling in the testicle, which may or may not be painful. Cancer can metastasize to nearby lymph nodes and other organs, such as the lungs, liver, and brain, as it grows. There are several types of testicular carcinoma, including seminomas and non-seminomas, and each type has a different rate of growth and response to treatment. Treatment options for testicular carcinoma include surgery, radiation therapy, and chemotherapy, and treatment choice depends on the cancer stage and the individual’s overall health. With early detection and appropriate treatment, the prognosis for testicular carcinoma is generally good, with a high survival rate. This paper will explore the impact of an undescended testicle on a young man’s risk for developing testicular cancer, the side effects of cytotoxic chemotherapy, the purpose of preserving the man’s sperms before chemotherapy, and finally look at the development of testicular carcinoma.

The Impact of an Undescended Testicle on the Young Man’s Risk for Developing Testicular Cancer

An undescended testicle, or cryptorchidism, is a condition where one or both testicles fail to descend into the scrotum during fetal development. This condition increases the risk of developing testicular cancer, as the undescended testicle(s) may be more prone to malignant transformation (Evie et al. 33). In fact, men with a history of cryptorchidism are three to four times more likely to develop testicular cancer than men without this condition. In the case of the 21-year-old male, he had a history of delayed descent of his right testicle until the age of 1-year-old. This suggests that he had cryptorchidism in the past, which increases his risk of developing testicular cancer. Moreover, his presenting symptoms and diagnostic workup were consistent with testicular cancer, specifically embryonal cell carcinoma, a germ cell tumour commonly associated with undescended testicles. It is important to note that not all cases of cryptorchidism result in testicular cancer, and not all testicular cancers are associated with cryptorchidism. However, the presence of undescended testicles is considered a risk factor for this type of cancer, and it is recommended that men with a history of cryptorchidism undergo regular testicular examinations and consider early intervention if testicular cancer is suspected (Wade et al. 785). The presence of an undescended testicle in this young man increased his risk of developing testicular cancer, which was subsequently diagnosed and treated through orchiectomy and chemotherapy. Regular surveillance and prompt medical attention may have prevented the development of metastatic disease and improved his long-term prognosis.

The Side Effects of Cytotoxic Chemotherapy

Cytotoxic chemotherapy is a treatment that uses drugs to kill cancer cells. While it can effectively treat cancer, it can also have several side effects. These side effects occur because chemotherapy targets rapidly dividing cells, including cancer and some healthy cells. One of the most common side effects of chemotherapy is hair loss (Rinky et al. 4). This occurs because hair follicle cells divide rapidly and are therefore targeted by chemotherapy drugs. Other rapidly dividing cells, such as those in the digestive tract, can also be affected, leading to nausea, vomiting, diarrhea, and mouth sores. Cytotoxic chemotherapy can also weaken the immune system, making it harder for the body to fight infections (Volker 412). This can increase the risk of infections, such as pneumonia or urinary tract infections. Additionally, chemotherapy can affect the production of blood cells in the bone marrow, leading to anemia, fatigue, and an increased risk of bleeding and bruising (Sangavi 3). Finally, chemotherapy can also have long-term effects on the body, such as an increased risk of developing second cancer later in life. It is essential for patients undergoing chemotherapy to be monitored closely by their healthcare providers and to report any side effects they experience so that they can be managed appropriately.

The Purpose of Preserving his Sperm before Chemotherapy

Preserving sperm before undergoing chemotherapy is a standard procedure for men diagnosed with testicular cancer, as chemotherapy can adversely affect their fertility. The chemotherapy drugs used to treat testicular cancer can damage the sperm-producing cells in the testicles, leading to temporary or permanent infertility (Marta et al. 145). In this case, the young man was only 21 years old, and preserving his sperm was crucial in ensuring his ability to have biological children in the future. Sperm banking, or cryopreservation, involves collecting and freezing a sample of semen, which can be used for artificial insemination or in vitro fertilization later. While the priority in treating testicular cancer is to eradicate and prevent it from spreading, preserving fertility is essential for young men who wish to have children (Jesse et al. 307). The process of sperm banking is simple and non-invasive and can be done before or after cancer treatment. Preserving sperm before chemotherapy is a standard procedure for men with testicular cancer, as it can help maintain their ability to have children. In this case, the young man’s decision to bank his sperm was wise, as it allowed him to focus on his treatment without worrying about the potential impact on his fertility.

The Development of Testicular Carcinoma

Testicular carcinoma is a relatively rare cancer that accounts for only about 1% of all cancers in men. Most cases occur in young and middle-aged men, with a peak incidence between the ages of 20 and 35 (Christof et al. 903). As such, the age of this young man, who is 21 years old, is typical for the development of testicular carcinoma. Risk factors for testicular carcinoma include a history of undescended testicle (cryptorchidism), a family history of testicular cancer, and personal history of testicular cancer (Louis et al. 8). This young man had a history of delayed descent of his right testicle until the age of 1-year-old, which is a known risk factor for the development of testicular carcinoma. However, it is essential to note that most cases of testicular carcinoma occur in men without any known risk factors. It is crucial to catch testicular carcinoma early to improve the chances of successful treatment (Ana et al. 1515). Self-examining the testicles is a simple and effective way to detect abnormalities, such as a lump or swelling, which a healthcare provider can further evaluate. In this case, the young man detected a grape-sized mass in his right testicle during self-examination, leading to early detection and prompt treatment. This young man’s age is typical for the development of testicular carcinoma, and early detection is crucial for successful treatment. Men of all ages should perform regular self-examinations of their testicles and seek medical attention promptly if any abnormalities are detected.


In conclusion, the case study of a 21-year-old male with testicular carcinoma highlights the importance of self-examination and prompt medical attention. The presence of an undescended testicle in infancy may increase the risk of developing testicular cancer in later life. The use of routine laboratory studies, ultrasound, and CT scans aided in diagnosing and treating this young man’s cancer. The chemotherapy regimen used to treat this patient may result in various side effects, such as hair loss, nausea, and fatigue. Therefore, preserving his sperm before chemotherapy was critical to ensure his fertility post-treatment. While testicular carcinoma typically affects men between the ages of 15 and 35, this young man’s case illustrates the importance of regular self-examination for men of all ages to detect and treat testicular cancer early. Overall, this case study underscores the need for increased awareness, early detection, and prompt treatment for testicular cancer to improve patient outcomes.



Works Cited

Bertram, Christof A., et al. “Neoplasia and tumor-like lesions in pet rabbits (Oryctolagus cuniculus): a retrospective analysis of cases between 1995 and 2019.” Veterinary Pathology 58.5 (2021): 901-911.

Fadich, Ana, et al. “USPSTF testicular examination nomination–self-examinations and examinations in a clinical setting.” American Journal of Men’s Health 12.5 (2018): 1510-1516.

Hanson, Brent M., Michael L. Eisenberg, and James M. Hotaling. “Male infertility: a biomarker of individual and familial cancer risk.” Fertility and sterility 109.1 (2018): 6-19. https://doi.org/10.1016/j.fertnstert.2017.11.005

Iniya Sangavi, S. Clinico Etiological Profile of Pancytopenia and Bicytopenia in Pediatric Population Aged 1 Month-12 Years at Tertiary Care Centre. Diss. Madras Medical College, Chennai, 2020.

Kapoor, Rinky, et al. “Evaluation of efficacy of QR678® and QR678® Neo hair growth factor formulation in the treatment of persistent chemotherapy‐induced alopecia caused due to cytotoxic chemotherapy—A prospective pilot study.” Journal of Cosmetic Dermatology 19.12 (2020): 3270-3279. https://doi.org/10.1111/jocd.13759

Leblanc, Louis, et al. “Testicular microlithiasis and testicular tumor: a review of the literature.” Basic and clinical andrology 28.1 (2018): 1-10.

Ljungman, L., et al. “Sexual dysfunction and reproductive concerns in young men diagnosed with testicular cancer: an observational study.” The journal of sexual medicine 16.7 (2019): 1049-1059. https://doi.org/10.1016/j.jsxm.2019.05.005

Mercieca-Bebber, Rebecca, et al. “Patient-reported outcomes associated with treatments for testicular cancer: a systematic review.” Patient Related Outcome Measures (2021): 129-171.

Muncey, Wade, et al. “Fertility potential in adult men treated for uncorrected bilateral cryptorchidism: A systematic literature review and analysis of case reports.” Andrology 9.3 (2021): 781-791. https://doi.org/10.1111/andr.12964

Ory, Jesse, et al. “Outcomes of organ‐sparing surgery for adult testicular tumors: A systematic review of the literature.” BJUI compass 2.5 (2021): 306-321. https://doi.org/10.1002/bco2.77

Schirrmacher, Volker. “From chemotherapy to biological therapy: A review of novel concepts to reduce the side effects of systemic cancer treatment.” International journal of oncology 54.2 (2019): 407-419. https://doi.org/10.3892/ijo.2018.4661

Tarasiewicz, Marta, et al. ““Oncofertility” procedures in children and adolescents.” Pediatric Endocrinology Diabetes and Metabolism 25.3 (2019): 144-149.

Yeap, Evie, Ramesh M. Nataraja, and Maurizio Pacilli. “Undescended testes:’What general practitioners need to know’.” Australian Journal of General Practice 48.1/2 (2019): 33-36.

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